Santee Homes for Sale

Santee Homes for Sale

Welcome to Santee, South Carolina, a charming town nestled in the heart of Orangeburg County. Known for its serene landscapes and warm Southern hospitality, Santee is a hidden gem that offers an idyllic lifestyle for families, retirees, and outdoor enthusiasts alike. With its picturesque views of Lake Marion, the largest lake in South Carolina, residents enjoy a plethora of recreational activities, from fishing and boating to hiking along scenic trails.

Santee boasts a friendly community atmosphere, making it easy to connect with neighbors and participate in local events. The town's rich history and cultural heritage are reflected in its quaint downtown area, where you can find delightful shops, restaurants, and cozy cafes. With its close proximity to major highways, Santee provides convenient access to larger cities like Columbia and Charleston, allowing residents to enjoy the tranquility of small-town living while still having urban amenities within reach.

When it comes to homes for sale in Santee, you'll find a diverse selection to suit every lifestyle and budget. From charming single-family homes with spacious yards to modern condos with stunning lake views, the real estate market in Santee has something for everyone. Many properties feature open floor plans, updated kitchens, and outdoor living spaces perfect for entertaining or relaxing after a day on the water.

Whether you’re looking for a vacation retreat or a permanent residence, Santee offers a unique blend of nature, community, and comfort. Explore the available homes for sale today and discover the perfect place to call home in this delightful Southern town!

Newest Santee Homes for Sale

$239,000
3 Beds ⋅ 2 Baths ⋅ 203985 MLS
Beautiful 2 year new 3bdrm, 2 full bath home has open floorplan and electric charging station in the single garage plus 2 car driveway parking in the heart of Santee only a couple minutes to Lake Marion, shopping, 3 golf courses and I-95. Approx. 1 hour to Charleston, Columbia or Florence. All major appliances are included. Possible mortgage assumption at 3.99% interest rate. Home is wired for Ring Security System. Like new condition.

764 Striped Bass Ct, Santee
$399,900
3 Beds ⋅ 3 Baths ⋅ 203879 MLS
Stunningly updated home offering a seamless blend of modern comfort, thoughtful design, and inviting indoor outdoor living. Set on a spacious .79 acres, tree lined property, this residence features 2141 sq ft of living space, 3 bedrooms, 2.5 bathrooms, beautifully finished interiors, multiple living spaces, and a backyard retreat complete with a pool and generous deck areas. Inside, the main living areas are bright and open, highlighted by large windows that frame views of the surrounding mature landscaping. Several living rooms provide flexible gathering spaces, from cozy fireplace seating with custom built-ins to airy lounge areas filled with natural light. The kitchen is a standout with deep blue cabinetry, gold hardware, granite counters, stainless appliances, and modern pendant lighting. An oversized island with seating opens directly to the dining area, where floor to ceiling windows overlook the backyard and pool. Bedrooms are spacious and serene, featuring large windows, and updated lighting. The bathrooms have been thoughtfully renovated with clean modern finishes, including pebble tile shower flooring, decorative tile accents, contemporary vanities, bronze and brushed nickel fixtures, and warm lighting. The laundry room offers additional storage with sleek black cabinetry and space for a washer and dryer on pedestals. Outdoor living is a major highlight. A wide wooden deck extends along the back of the home, offering multiple seating zones perfect for relaxing or hosting. The front covered porch provides shade and comfort with views of the surrounding landscaping. The pool area includes a concrete surround, perfect for sunbathing. An aerial view showcases the generous lot size, and the overall privacy of the property. With its cohesive design, updated finishes, abundant natural light, and inviting outdoor spaces, this home delivers a move in ready experience in a peaceful setting. This home is ideally positioned in Santee, a peaceful lakeside community known for its natural beauty, outdoor recreation, and easy access to the best of the Charleston region. Just minutes away is Lake Marion, one of South Carolina's largest and most beloved lakes, offering boating, fishing, kayaking, and scenic waterfront parks. The area is also home to golf courses, nature trails, and quiet residential streets that create a relaxed, welcoming environment. Santee provides a comfortable small town feel while still offering quick access to major conveniences. Local shops, restaurants, and everyday services are close by, and I-95 is only a short drive, making travel simple. For those who commute or enjoy spending time in Charleston, the home sits roughly an hour from downtown, close enough to enjoy the city's dining, shopping, beaches, and historic districts, yet far enough to maintain the tranquility of lakeside living. With its beautifully updated interior, inviting outdoor spaces, and a location that balances peaceful living with regional accessibility, 1010 Park Dr offers a rare combination of comfort, style, and convenience.

1010 Park Dr, Santee
$235,000
3 Beds ⋅ 2 Baths ⋅ 203721 MLS
Lake life! Welcome to the Bluffs in Santee! This Lake Marion community offers rural living just minutes from I95. As a full time, retirement or possible VRBO investment. This recently updated home features 3 bed rooms, 2 full baths, a spacious kitchen, a nice sized living room, new appliances and plenty of off street parking! Minutes from shopping, restaurants, State Park, Water Park and boat launches!

130 2nd St, Santee
$228,000
4 Beds ⋅ 2 Baths ⋅ 203647 MLS
Great deal in a great area!!! Center Pointe is located in the heart of Santee, South Carolina Minutes from I 95 and close to boat access. Golf Destinations and country living surrounds this 4-bedroom 2 bath home that boast an open kitchen and ample yard space.

143 William Clark Blvd, Santee
$379,900
3 Beds ⋅ 2 Baths ⋅ 203351 MLS
Welcome to Santee Cooper Resort, where golf, lake living, and Lowcountry charm come together. This well-maintained 3-bedroom, 2-bath home overlooks the 13th and 14th holes of Santee Cooper Country Club, offering beautiful fairway views from your own backyard. Enjoy quick access to Lake Marion for boating, fishing, and watersports, along with championship golf just steps away. Conveniently located off I-95, you're less than an hour from the Charleston area, making it easy to enjoy the coast's dining, shopping, and attractions without the everyday traffic. Whether you're searching for a primary residence, vacation home, or investment property, this home offers the lifestyle you've been looking for. Give me a call to set up your private tour!

106 Wateree Dr, Santee
$589,000
3 Beds ⋅ 2 Baths ⋅ 203254 MLS
Enjoy country living on this 9.47-acre property in a brick home (2,269sf) 3BR/2BA built in 1983 with all improvements. Home is move-in ready! Enjoy nature walks among the beautiful trees leading to a spring fed creek. Seller has installed a culvert to drive over, and a removable dam, as needed, to form a pond for great wood duck hunting. Property is home to the deer and other wildlife. The seller is quite proud of his hunting skill as you can tell by the deer heads mounted in his residence. Lots of open space for pets/animals. Metal roof in 2021 w/acrylab acrylic coating. Gutter added in 2025. Large kitchen with lots of cabinets for storage. Soaking tub w/heated towel bar. Spacious laundry room. Water softener system. High speed fiber internet. Entire house Peerless Gas Boiler system, wired on two zones to baseboard heat with programmable controller and fireplace with Appalachian stove insert and blower system.

138 Heatleys End Rd, Santee
$570,000
4 Beds ⋅ 4 Baths ⋅ 203164 MLS
Welcome to 370 Chapel Creek Drive in Santee, SC, where golf, lake living, and Lowcountry charm come together in one exceptional property. This beautifully crafted 4-bedroom, 4-bathroom brick home offers approximately 3,720 square feet of thoughtfully designed living space on a spacious 0.81-acre lot overlooking a peaceful pond in the desirable Chapel Creek community. Ideally located just a golf cart ride from Santee National Golf Club and only minutes from Santee Cooper Country Club and Lake Marion Golf Course, this home offers convenient access to three outstanding golf courses. Lake Marion, South Carolina's largest lake, is also just minutes away, providing endless opportunities for boating, fishing, kayaking, and year-round outdoor recreation. Inside, the home welcomes you with a bright, open floor plan highlighted by vaulted ceilings, abundant natural light, and a spacious living area centered around a fireplace. The kitchen serves as the heart of the home, featuring an oversized island, white cabinetry, stone countertops, tiled backsplash, stainless steel appliances, and a dedicated pantry/coffee bar, creating an ideal space for both everyday living and entertaining. The main-level primary suite offers a private retreat with direct access to the back deck and peaceful water views. The en-suite bathroom features dual vanities, a jetted soaking tub, a tiled walk-in shower, and generous storage. Two additional bedrooms are located on the main level, while the upstairs bedroom with a private full bath provides flexible space for guests, a home office, recreation room, or additional living area. Outdoor living is equally impressive with an expansive deck designed for entertaining or relaxing while overlooking the pond. A covered section extends the outdoor living space throughout the year, while the shaded patio below offers additional room to enjoy the surrounding natural setting. Mature trees provide privacy and enhance the tranquil backyard atmosphere. The oversized 2.5-car garage offers ample storage for vehicles, recreational equipment, and a golf cart, making it easy to enjoy the community and nearby amenities. Conveniently located near shopping, dining, Santee State Park, I-95, and the recreational opportunities of Lake Marion, this property offers an exceptional combination of comfort, convenience, and access to some of the area's most desirable golf and waterfront destinations.

370 Chapel Creek Dr, Santee
$274,900
3 Beds ⋅ 2 Baths ⋅ 202134 MLS
Charming 3-bedroom, 2-bath ranch in the quiet, gated 55+ community of Bradford Village. This well-designed home offers a split floor plan and a cozy double-sided fireplace. Features include a spacious wet bar, dedicated laundry room, private patio, and a workshop located behind the one-car garage with ample storage. Enjoy an active lifestyle with community amenities such as a pool, tennis courts, clubhouse, shuffleboard, and regular social events. Conveniently located just minutes from Santee Cooper Lake for boating and fishing.

23 Peter Collinson Rd, Santee
$1,300,000
6 Beds ⋅ 6 Baths ⋅ 201806 MLS
First time on the market, this exceptional custom-built lakefront home is a rare offering in the gated community of Santee Cooper Resort on Lake Marion. Designed to showcase sweeping big-water views, the home is filled with dramatic architectural details, including soaring ceilings and walls of picture windows that flood the space with natural light. The main level is both elegant and functional, featuring hardwood floors throughout, a stunning foyer, formal dining room, library, wet bar, breakfast room, and a beautifully appointed kitchen. The owner's suite is also on the main level and offers direct access to a walkout balcony, perfect for morning coffee overlooking the lake. A sunroom opens to the outdoors, seamlessly connecting indoor and outdoor living, while the charming front courtyard adds privacy and curb appeal. Upstairs, plush white carpeting leads to three spacious bedrooms, offering incredible flexibility. The water-front bedroom features a private en-suite and could easily serve as a second primary or in-law suite, complete with an exclusive balcony. The two bedrooms on the front side of the home, share a jack-and-Jill style bath. The far-right bedroom is connected to a large, finished room over the garage—ideal for a private dressing room, exercise space, sewing room, or office. The full walkout basement expands the living space dramatically and is perfect for guests or multi-generational living. It includes a second kitchen, a bathroom with laundry hookup, a large bedroom with walk-in closet, an additional bedroom, built-in bookshelves, living room with a cozy wood-burning fireplace, and a spacious game room with sliding glass doors that open to a covered patio. Step outside to your refinished private dock and enjoy direct access to Lake Marion. Residents of Santee Cooper Resort enjoy access to golf, swimming pool, tennis courts, and the peace of mind of a gated community. This is lake living at its finest—custom craftsmanship, flexible living spaces, and unforgettable views!

443 Santee Dr, Santee
$549,000
3 Beds ⋅ 3 Baths ⋅ 200855 MLS
This beautiful brick home is perfectly situated on the scenic Santee Cooper Golf Course, offering serene views and peaceful living within the gated Santee Cooper Resort. Listed UNDER appraised value! This charming residence offers the perfect blend of comfort and style. Inside, you'll find a newly renovated kitchen and bathrooms, thoughtfully designed with modern finishes and functionality in mind. The home features a spacious FROG, ideal for a guest suite, office, or recreation space, and a large attic that can easily be finished to add even more living area. Enjoy resort-style living with neighborhood amenities including boat storage, boat slips, a private boat ramp, and a community dock—perfect for lake lovers. Residents also have access to tennis courts and a community pool available with a separate membership. Golf, water, and lifestyle all in one! Live where you play! Call me today to set up your private tour! Seller will pay the buyers initiation fee with an acceptable offer!

126 Wateree Dr, Santee
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